Archival Overview
Pioneering African American chemist who developed total chemical synthesis of physostigmine for glaucoma and scalable plant-based synthesis of steroid hormones such as cortisone and progesterone.
Biographical Record
Percy Lavon Julian (1899–1975) triumphed over Jim Crow segregation to graduate valedictorian from DePauw University and earn his doctorate at the University of Vienna. In 1935, he completed the world's first total synthesis of physostigmine, a breakthrough medicine for glaucoma.
At the Glidden Company, Julian extracted stigmasterol from soybeans to synthesize progesterone and cortisone at a fraction of their historical cost, making treatment for rheumatoid arthritis universally affordable. He registered more than 130 chemical patents.
Key Life Milestones
Total Synthesis of Physostigmine
Synthesized the glaucoma therapeutic drug physostigmine from fundamental precursors.
Low-Cost Cortisone Synthesis
Engineered industrial extraction of Compound S from soybean sterols, making cortisone accessible.
Memorial Guestbook & Tributes
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Final Resting Place
Perpetual MemorialRiver Grove (Illinois), United States