Archival Overview
Pioneering French immunologist who won the 1980 Nobel Prize in Physiology or Medicine for discovering the Major Histocompatibility Complex (HLA system) in humans, revolutionizing organ transplantation and genetic disease susceptibility.
Biographical Record
Mobilized as an ambulance officer in World War II, Dausset served with Free French forces in North Africa, performing battlefield blood transfusions. Joining the Saint-Louis Hospital in Paris, he studied leuco-agglutination in patients receiving repeated transfusions.
In 1958, Dausset discovered the first human leukocyte antigen (MAC, now HLA-A2), proving that humans possess genetically determined tissue antigens that determine whether transplanted organs (kidneys, hearts) are accepted or rejected. In 1984, using his Nobel Prize funds, he founded the Centre d'Étude du Polymorphisme Humain (CEPH), contributing to mapping the human genome.
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Final Resting Place
Perpetual MemorialParis, France