Archival Overview
Belgian cytologist and biochemist who shared the 1974 Nobel Prize in Physiology or Medicine with Albert Claude and George Palade for discovering lysosomes and peroxisomes, revolutionizing cell biology.
Biographical Record
Born in England to Belgian refugee parents during World War I, De Duve graduated in medicine and chemistry from the Catholic University of Leuven. While investigating the intracellular mechanism of insulin, he pioneered rate-zonal cell fractionation by differential centrifugation.
In 1955, De Duve discovered lysosomes, the membrane-bound 'recycling centers' and digestive organelles of the cell, and later discovered peroxisomes. In 1974, he founded the International Institute of Cellular and Molecular Pathology (now the de Duve Institute) in Brussels.
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Final Resting Place
Perpetual MemorialGrez-Doiceau (Walloon Brabant), Belgium